Associate Director, Johns Hopkins Myositis Center
Sonye Danoff is a Professor of Medicine in the Division of Pulmonary and Critical Care Medicine, Co-Director of the Interstitial Lung Disease Program, and Associate Director of the Myositis Center at Johns Hopkins University School of Medicine, Baltimore, USA. A Phi Beta Kappa graduate of Emory University, she received her MPhil in Pharmacology from Cambridge University and an MD-PhD from Johns Hopkins University School of Medicine. Dr. Danoff is actively involved in patient care, teaching and research in ILD with a focus on autoimmune-associated ILDs. Her research involves clinical and translational studies of lung fibrosis and autoimmunity. She is a Fellow of the American College of Chest Physicians and past Chair of the Interstitial and Diffuse Lung Disease Network Steering Committee. She is a member of the American Thoracic Society and past Chair of the Clinical Problems Assembly Program Committee.
Her research focuses on basic and translational studies of lung fibrosis. She was awarded the 2007 American Thoracic Society/Coalition for Pulmonary Fibrosis Research Award to support her research studies.
She has also been a recipient of grants from the National Institutes of Health, the Mid-Atlantic American Heart Association and the American Lung Association.
- MD: Johns Hopkins University, School of Medicine
- PhD: Johns Hopkins University, School of Medicine
- Post-doctoral Fellowship: Johns Hopkins University, School of Medicine, Pulmonary and Critical Care Medicine
- Internship and Residency: Johns Hopkins Hospital
Selected Recent Original Research Publications:
- Rebuttal From Drs Oldham and Danoff. Oldham JM, Danoff SK.
Chest. 2019 Feb;155(2):264-265. doi: 10.1016/j.chest.2018.08.1071. No abstract available.
- COUNTERPOINT: Does Interstitial Pneumonia With Autoimmune Features Represent a Distinct Class of Patients With Idiopathic Interstitial Pneumonia? No. Oldham JM, Danoff SK.
Chest. 2019 Feb;155(2):260-263. doi: 10.1016/j.chest.2018.08.1073.
- Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease-Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities. Fischer A, Strek ME, Cottin V, Dellaripa PF, Bernstein EJ, Brown KK, Danoff SK, Distler O, Hirani N, Jones KD, Khanna D, Lee JS, Lynch DA, Maher TM, Millar AB, Raghu G, Silver RM, Steen VD, Volkmann ER, Mullan RH, O’Dwyer DN, Donnelly SC. QJM. 2019 Feb 1;112(2):81-93. doi: 10.1093/qjmed/hcy272.
- Muscular and extramuscular clinical features of patients with anti-PM/Scl autoantibodies. De Lorenzo R, Pinal-Fernandez I, Huang W, Albayda J, Tiniakou E, Johnson C, Milisenda JC, Casal-Dominguez M, Corse AM, Danoff SK, Christopher-Stine L, Paik JJ, Mammen AL.
Neurology. 2018 Jun 5;90(23):e2068-e2076. doi: 10.1212/WNL.0000000000005638. Epub 2018 May 4.
- The effect of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis. Schiffenbauer A, Faghihi-Kashani S, O’Hanlon TP, Flegel WA, Adams SD, Targoff IN, Oddis CV, Ytterberg SR, Aggarwal R, Christopher-Stine L, Shamim EA, Dellaripa PF, Danoff SK, Mammen AL, Miller FW.
Semin Arthritis Rheum. 2018 Dec;48(3):504-512. doi: 10.1016/j.semarthrit.2018.02.003. Epub 2018 Feb 14.
- Myositis: Prognostic factors in ‘pneumo-myositis’. Danoff SK.
Nat Rev Rheumatol. 2018 May;14(5):253-254. doi: 10.1038/nrrheum.2018.55. Epub 2018 Apr 12.
- Exploration of the MUC5B promoter variant and ILD risk in patients with autoimmune myositis. Johnson C, Rosen P, Lloyd T, Horton M, Christopher-Stine L, Oddis CV, Mammen AL, Danoff SK.
Respir Med. 2017 Sep;130:52-54. doi: 10.1016/j.rmed.2017.07.010. Epub 2017 Jul 17.
- A Standardized Diagnostic Ontology for Fibrotic Interstitial Lung Disease. An International Working Group Perspective. Ryerson CJ, Corte TJ, Lee JS, Richeldi L, Walsh SLF, Myers JL, Behr J, Cottin V, Danoff SK, Flaherty KR, Lederer DJ, Lynch DA, Martinez FJ, Raghu G, Travis WD, Udwadia Z, Wells AU, Collard HR.
Am J Respir Crit Care Med. 2017 Nov 15;196(10):1249-1254. doi: 10.1164/rccm.201702-0400PP.
- A longitudinal cohort study of the anti-synthetase syndrome: increased severity of interstitial lung disease in black patients and patients with anti-PL7 and anti-PL12 autoantibodies. Pinal-Fernandez I, Casal-Dominguez M, Huapaya JA, Albayda J, Paik JJ, Johnson C, Silhan L, Christopher-Stine L, Mammen AL, Danoff SK.
Rheumatology (Oxford). 2017 Jun 1;56(6):999-1007. doi: 10.1093/rheumatology/kex021.